Article
HLA antigens and primary osteoarthritis of the hand.
The Journal of rheumatology - 1 Jun 2003
Merlotti Daniela, Santacroce Clorinda, Gennari Luigi, Geraci Simone, Acquafredda Vincenzo, Conti Tullio, Bargagli Gianluca, Canto Norberto Dal, Biagi Federica, Gennari Carlo, Giordano Nicola
Abstract excerpt
OBJECTIVE: Many studies have examined genetic factors associated with either development or severity of primary osteoarthritis (OA). Analyses of the frequencies of HLA antigens in various OA populations have yielded conflicting results; an increased frequency of HLA-A1, B8, and DR4 alleles has been suggested. We investigated the interrelationship between HLA antigens and primary OA. METHODS: We analyzed the...
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