Article
Allelotyping of human prostatic adenocarcinoma.
Genomics - 1 Nov 1991
Kunimi K, Bergerheim U S, Larsson I L, Ekman P, Collins V P
Abstract excerpt
Allelotyping (using at least one probe detecting a restriction fragment length polymorphism on each chromosomal arm, with the exception of the short arms of the acrocentric chromosomes), showed loss of genetic information in 11 of 18 prostate adenocarcinoma specimens analyzed (61%). Frequent allelic deletions were detected on the long arm of chromosome 16 (6 of 10 informative cases, 60%), on the short arm of...
Topics
- Adenocarcinoma
- Aged
- Alleles
- Blotting, Southern
- Chromosome Deletion
- Chromosome Mapping
- DNA Probes
- Genotype
- Humans
- Male
- Middle Aged
- Polymorphism, Restriction Fragment Length