Article
Characterization of genetically diverse HIV type 1 from a London cohort: near full-length genomic analysis of a subtype H strain.
AIDS research and human retroviruses - 1 Jul 2009
Holzmayer Vera, Aitken Celia, Skinner Celia, Ryall Laura, Devare Sushil G, Hackett John
Abstract excerpt
HIV-1 is characterized by an exceptional level of sequence diversity and a rapid rate of evolution. HIV diversity has implications for reliability of assays designed to detect and monitor infection, pathogenesis, disease progression, response to antiviral therapeutics, resistance pathways, and vaccine development. In the present study, HIV-1 strain diversity was assessed for a small clinical cohort (n = 15) from...
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