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Article

A trapped intracellular cation modulates K+ channel recovery from slow inactivation.

The Journal of general physiology - 1 Aug 2006

Ray Evan C, Deutsch Carol

Abstract excerpt

Upon depolarization, many voltage-gated potassium channels undergo a time-dependent decrease in conductance known as inactivation. Both entry of channels into an inactivated state and recovery from this state govern cellular excitability. In this study, we show that recovery from slow inactivation is regulated by intracellular permeant cations. When inactivated channels are hyperpolarized, closure of the...

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Identifiers

PMID: 16847099
DOI: 10.1085/jgp.200609561
PMCID: PMC2151525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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