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Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

30 Jan 2019

Abstract excerpt

Spatially ordered embryo-like structures self-assembled from blastocyst-derived stem cells can be generated to mimic embryogenesis in vitro. However, the assembly system and developmental potential of such structures needs to be further studied. Here, we devise a nonadherent-suspension-shaking system to generate self-assembled embryo-like structures (ETX-embryoids) using mouse embryonic, trophoblast and...

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PMID: 30700702
DOI: 10.1038/s41467-019-08378-9

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