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Article

Fatty acids bound to human serum albumin and its structural variants modulate apolipoprotein B secretion in HepG2 cells.

Biochimica et biophysica acta - 1 Jul 2006

Ha Ji-Sook, Theriault Andre, Bhagavan Nadhipuram V, Ha Chung-Eun

Abstract excerpt

Epidemiologic studies have shown an inverse relationship between human serum albumin (HSA) levels and coronary heart disease (CHD). However, no mechanisms have been identified to explain this relationship. We hypothesized that this relationship is due to differences in binding affinity of fatty acids to HSA and subsequent atherogenic lipoprotein synthesis and secretion from hepatocytes. To test our hypothesis we...

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Source

Identifiers

PMID: 16843720
DOI: 10.1016/j.bbalip.2006.05.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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