Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in the human ApoB signal peptide modulates ApoB17 translocation.

Biochemical and biophysical research communications - 27 Apr 2001

Benhizia F, Ginsberg H N, Humphries S E, Talmud P J

Abstract excerpt

The functional effects of the common 27- or 24-amino-acid (aa) variants in the human apoB signal peptide (SP) on intracellular and secreted apoB17 were investigated in vitro. Only in the presence of oleate was a significant difference in intracellular and secreted SP27-B17 compared to SP24-B17 observed (P = 0.01 and P < 0.0007, respectively), although in the presence or absence of oleate mRNA levels from the two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins B
Share to Cell Fractionation
Share to COS Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytosol

Share to Intracellular Fluid

Share to Microsomes

Share to Oleic Acid

Share to Protein Sorting Signals

Source

Identifiers

PMID: 11322782
DOI: 10.1006/bbrc.2001.4740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in the human ApoB signal peptide modulates ApoB17 translocation.PMID 11322782Read ↗

A role for palmitoylation in the quality control, assembly and secretion of apolipoprotein B.Semantic proximity Read ↗

Human apolipoprotein B signal sequence variants confer a secretion-defective phenotype when expressed in yeast.Semantic proximity Read ↗

Fatty acids bound to human serum albumin and its structural variants modulate apolipoprotein B secretion in HepG2 cells.Semantic proximity Read ↗

A Novel Nontruncating APOB Gene Mutation, R463W, Causes Familial HypobetalipoproteinemiaSemantic proximity Read ↗

Apo B signal peptide insertion/deletion polymorphism is involved in postprandial lipoparticles' responses.Semantic proximity Read ↗

Characterization of a mutant form of human apolipoprotein B (Thr26_Tyr27del) associated with familial hypobetalipoproteinemia.Semantic proximity Read ↗

Apolipoprotein B signal peptide and apolipoprotein E genotypes as determinants of the hepatic secretion of VLDL apoB in obese men.Semantic proximity Read ↗

Structural and functional consequences of the Milano mutation (R173C) in human apolipoprotein A-I.Semantic proximity Read ↗

Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER.Semantic proximity Read ↗

Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux.Semantic proximity Read ↗

Postprandial lipemia in subjects with hypobetalipoproteinemia and a single intestinal allele for apoB-48.Semantic proximity Read ↗

A common apolipoprotein B signal peptide polymorphism modifies the relation between plasma non-esterified fatty acids and triglyceride concentration in men.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.