Diagnostic utility of oncogenes and their products in human cancer.

doi:10.1016/0304-419x(91)90014-c

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Article

Diagnostic utility of oncogenes and their products in human cancer.

Biochimica et biophysica acta - 10 Dec 1991

McKenzie S J

Abstract excerpt

The first clear cut association of an oncogene with a specific cancer is the c-abl translocation in chronic myelogenous leukemia and acute lymphocytic leukemia; it has been observed in 90% of CML cases examined. This is the major contributing factor to its being the target of the first oncogene-b...

Topics

Female
Genes, Tumor Suppressor
Genes, abl
Genes, myc
Genes, ras
Humans
Mutation
Neoplasms
Oncogenes
Proto-Oncogene Proteins
Proto-Oncogenes
Receptor, ErbB-2

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