Article
One-step immobilization of poly(dT)-modified DNA onto non-modified plastic substrates by UV irradiation for microarrays.
Biochemical and biophysical research communications - 25 Aug 2006
Kimura Naoki
Abstract excerpt
Previously, 'DNattach', an alternative DNA immobilization system for attaching modified oligonucleotide probes onto a gold surface by UV irradiation that can be used in various DNA microarray applications including gene expression analysis, was developed. Attached to the gold surface, the modified probes have been shown to successfully detect synaptogenesis in the developing mouse cerebellum. In this study, this...
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