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Article

A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands.

Genome research - 1 Aug 2006

Giallourakis Cosmas, Cao Zhifang, Green Todd, Wachtel Heather, Xie Xiaohui, Lopez-Illasaca Marco, Daly Mark, Rioux John, Xavier Ramnik

Abstract excerpt

PDZ domain-containing proteins and their interaction partners are mutated in numerous human diseases and function in complexes regulating epithelial polarity, ion channels, cochlear hair cell development, vesicular sorting, and neuronal synaptic communication. Among several properties of a collection of documented PDZ domain-ligand interactions, we discovered embedded in a large-scale expression data set the...

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Identifiers

PMID: 16825666
DOI: 10.1101/gr.5285206
PMCID: PMC1524865

Genes

CARD11
DLG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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