Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology.

The Journal of molecular diagnostics : JMD - 1 Jul 2006

Parr Ryan L, Dakubo Gabriel D, Crandall Keith A, Maki Jennifer, Reguly Brian, Aguirre Andrea, Wittock Roy, Robinson Kerry, Alexander Jude S, Birch-Machin Mark A, Abdel-Malak Mamdouh, Froberg M Kent, Diamandis Eleftherios P, Thayer Robert E

Abstract excerpt

Studies of somatic mitochondrial DNA mutations have become an important aspect of cancer research because these mutations might have functional significance and/or serve as a biosensor for tumor detection. Here we report somatic mitochondrial DNA mutations from three specific tissue types (tumor, adjacent benign, and distant benign) recovered from 24 prostatectomy samples. Needle biopsy tissue from 12 individuals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy, Fine-Needle
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to DNA Mutational Analysis

Share to Pilot Projects

Share to Prostate

Share to Prostatic Hyperplasia

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 16825503
DOI: 10.2353/jmoldx.2006.050112
PMCID: PMC1867611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology.PMID 16825503Read ↗

Mitochondrial mutations in early stage prostate cancer and bodily fluids.Semantic proximity Read ↗

Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.Semantic proximity Read ↗

Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical managementSemantic proximity Read ↗

Mitochondria, prostate cancer, and biopsy sampling error.Semantic proximity Read ↗

Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer.Semantic proximity Read ↗

Mitochondrial mutations drive prostate cancer aggressionSemantic proximity Read ↗

Tissue Sources for Accurate Measurement of Germline DNA Genotypes in Prostate Cancer Patients Treated With Radical Prostatectomy.Semantic proximity Read ↗

Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis.Semantic proximity Read ↗

Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection.Semantic proximity Read ↗

Mitochondrial DNA as a potential tool for early cancer detection.Semantic proximity Read ↗

Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men.Semantic proximity Read ↗

Reduced Mitochondrial DNA Content Associates with Poor Prognosis of Prostate Cancer in African American MenSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.