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Article

Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection.

Cancer research - 15 Nov 2002

Chen Junjian Z, Gokden Neriman, Greene Graham F, Mukunyadzi Perkins, Kadlubar Fred F

Abstract excerpt

Prostate cancer is the second leading cause of cancer deaths among men in the United States,but the precise molecular events leading to prostate carcinogenesis are not well understood. We isolated histologically defined cell populations from prostate cancer and its preinvasive lesions using laser capture microdissection, and performed genetic analysis on the mitochondrial genome, a sensitive cytoplasmic DNA. An...

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PMID: 12438238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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