Article
Sequence-based methods for identifying epidemiologically linked herpes simplex virus type 2 strains.
Journal of clinical microbiology - 1 Jul 2006
Martin Emily Toth, Koelle David M, Byrd Benjamin, Huang Meei-Li, Vieira Jeffrey, Corey Lawrence, Wald Anna
Abstract excerpt
Traditional methods for confirming the identity of herpes simplex virus (HSV) isolates use restriction fragment length polymorphism (RFLP). However, RFLP is less amenable to high-throughput analyses of many samples, and the extent to which small differences in RFLP patterns distinguish between different viral strains remains unclear. Viral HSV type 2 (HSV-2) DNA isolates from 14 persons experiencing a primary...
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