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Article

Utilization of microsatellite polymorphism for differentiating herpes simplex virus type 1 strains.

Journal of clinical microbiology - 1 Mar 2009

Deback C, Boutolleau D, Depienne C, Luyt C E, Bonnafous P, Gautheret-Dejean A, Garrigue I, Agut H

Abstract excerpt

The herpes simplex virus type 1 (HSV-1) genome is a linear double-stranded DNA of 152 kpb. It is divided into long and short regions of unique sequences termed U(L) and U(S), respectively, and these are flanked by regions of inverted internal and terminal repeats. Microsatellites are short tandem repeats of 1- to 6-nucleotide motifs; they are often highly variable and polymorphic within the genome, which raises...

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Identifiers

PMID: 19109460
DOI: 10.1128/JCM.01565-08
PMCID: PMC2650923

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