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Article

Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness.

Breast cancer research and treatment - 1 Sept 2002

D'Assoro Antonino B, Barrett Susan L, Folk Christopher, Negron Vivian C, Boeneman Kelly, Busby Robert, Whitehead Clark, Stivala Franca, Lingle Wilma L, Salisbury Jeffrey L

Abstract excerpt

Molecular mechanisms leading to genomic instability and phenotypic variation during tumor development and progression are poorly understood. Such instability represents a major problem in the management of breast cancer because of its contribution to more aggressive phenotypes as well as chemoresistance. In this study we analyzed breast carcinomas and tumor-derived cell lines to determine the relationship between...

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Identifiers

PMID: 12500932
DOI: 10.1023/a:1016550619925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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