Article
Analysis of single nucleotide polymorphism sites in exon 4 of the p53 gene using high-performance liquid chromatography electrospray ionization mass spectrometry tandem mass spectrometry.
European journal of mass spectrometry (Chichester, England) - 1 Jan 2006
Song Renfang, Zhang Wenbing, Chen Huayong, Ma Humin, Dong Yulian, Shen Guoying, Zhou Zhen
Abstract excerpt
Three groups of four oligonucleotides with special single nucleotide polymorphisms (SNP) sites in exon 4 of the p53 gene were analyzed with ion-pair reversed-phase high-performance liquid chromatography electrospray ionization mass spectrometry tandem mass spectrometry. The retention order of four oligonucleotides with SNPs was C < G < A < T, regardless of whether the polymorphisms were at the 3' end, the 5' end,...
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