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Article

Human monocyte-derived dendritic cells differentiated in the presence of IL-2 produce proinflammatory cytokines and prime Th1 immune response.

Journal of leukocyte biology - 1 Sept 2006

Sanarico Nunzia, Ciaramella Antonio, Sacchi Alessandra, Bernasconi Daniela, Bossù Paola, Mariani Francesca, Colizzi Vittorio, Vendetti Silvia

Abstract excerpt

Interleukin (IL)-2 plays an important role in the control of the immune responses, and it is released in a variety of tissues in response to inflammatory stimuli. As monocytes and mature dendritic cells (DCs) express CD25, the high-affinity subunit of IL-2 receptor, we examined the effect of exogenous IL-2 on the in vitro generation and maturation of DCs from monocytes. Human monocyte-derived DCs (MDDCs) were...

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PMID: 16809642
DOI: 10.1189/jlb.1105690

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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