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Article

FLT3 internal tandem duplication in CD34+/CD33- precursors predicts poor outcome in acute myeloid leukemia.

Blood - 15 Oct 2006

Pollard Jessica A, Alonzo Todd A, Gerbing Robert B, Woods William G, Lange Beverly J, Sweetser David A, Radich Jerald P, Bernstein Irwin D, Meshinchi Soheil

Abstract excerpt

Acute myeloid leukemia (AML) is a clonal disease characterized by heterogeneous involvement of hematopoietic stem cell/progenitor cell populations. Using FLT3 internal tandem duplication (FLT3/ITD) as a molecular marker, we tested the hypothesis that clinical outcome in AML correlates with disease involvement of CD34(+)/CD33(-) precursors. Diagnostic specimens from 24 children with FLT3/ITD-positive AML were...

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Identifiers

PMID: 16809615
DOI: 10.1182/blood-2006-04-012260
PMCID: PMC1895585

Genes

FLT3
EFS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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