Article
Immunophenotypic findings in acute myeloid leukemia with FLT3 internal tandem duplication.
Haematologica - 1 Jun 2003
Muñoz Luz, Aventín Ana, Villamor Neus, Juncà Jordi, Acebedo Gemma, Domingo Alicia, Rozman María, Torres J Pio, Tormo Mar, Nomdedéu Josep F
Abstract excerpt
BACKGROUND AND OBJECTIVES: The biological characteristics and the prognostic significance of the internal tandem duplication of the FLT3 (FLT3/ITD) were investigated in a series of de novo acute myeloid leukemia (AML) patients. One hundred and fifty-six adult patients with AML were included in the study. FLT3/ITD was detected in 41 (26%) patients (FLT3/ITD(+)). DESIGN AND METHODS: The main differences observed...
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