Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The prolactin-deficient mouse has an unaltered metabolic phenotype.

Endocrinology - 1 Oct 2006

LaPensee Christopher R, Horseman Nelson D, Tso Patrick, Brandebourg Terry D, Hugo Eric R, Ben-Jonathan Nira

Abstract excerpt

Prolactin (PRL), best recognized for its lactogenic activity, is also involved in the regulation of metabolic homeostasis in both mammalian and nonmammalian species. Although several mouse models have been used to study the metabolic functions of PRL, a clear-cut consensus has not emerged given the limited and often conflicting data. To clarify the role of PRL in metabolic homeostasis in males and nonlactating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adiponectin
Share to Diet, Fat-Restricted
Share to Dietary Fats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Intolerance

Share to Glucose Tolerance Test

Share to Lipolysis

Share to Metabolism

Share to Prolactin

Source

Identifiers

PMID: 16809445
DOI: 10.1210/en.2006-0487

Genes

PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The prolactin-deficient mouse has an unaltered metabolic phenotype.PMID 16809445Read ↗

Implications of multiple phenotypes observed in prolactin receptor knockout mice.Semantic proximity Read ↗

What Can We Learn from Rodents about Prolactin in Humans?Semantic proximity Read ↗

Pregnancy Hyperglycemia in Prolactin Receptor Mutant, but Not Prolactin Mutant, Mice and Feeding-Responsive Regulation of Placental Lactogen Genes Implies Placental Control of Maternal Glucose Homeostasis.Semantic proximity Read ↗

Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2.Semantic proximity Read ↗

Completely humanizing prolactin rescues infertility in prolactin knockout mice and leads to human prolactin expression in extrapituitary mouse tissues.Semantic proximity Read ↗

Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy.Semantic proximity Read ↗

Litter Size Reduction as a Model of Overfeeding during Lactation and Its Consequences for the Development of Metabolic Diseases in the OffspringSemantic proximity Read ↗

From the molecular biology of prolactin and its receptor to the lessons learned from knockout mice models.Semantic proximity Read ↗

Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice.Semantic proximity Read ↗

A prolactin family paralog regulates reproductive adaptations to a physiological stressor.Semantic proximity Read ↗

Lipoprotein Receptor LRP1 Regulates Leptin Signaling and Energy Homeostasis in the Adult Central Nervous SystemSemantic proximity Read ↗

Selective disruption of dopamine D2 receptors in pituitary lactotropes increases body weight and adiposity in female mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.