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Article

Immunohistochemical analysis of p53 and HER-2/neu proteins in human tumors.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Sept 1991

Chang K, Ding I, Kern F G, Willingham M C

Abstract excerpt

We examined samples of tumors of human breast, ovary, and colon of various degrees of malignancy for the expression of p53 protein, using a panel of anti-p53 antibodies and peroxidase immunohistochemistry. Of 66 tumor cases (24 cases of ovarian carcinoma, 23 cases of colon adenocarcinoma, and 19 cases of breast carcinoma), 36 (53%) showed high levels of expression of p53 using a human-specific antibody, and 16...

Topics

Breast Neoplasms
Colonic Neoplasms
Female
Humans
Immunoenzyme Techniques
Mutation
Neoplasms
Oncogene Proteins, Viral
Ovarian Neoplasms
Receptor, ErbB-2
Tumor Suppressor Protein p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1680897
DOI: 10.1177/39.9.1680897

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1680897-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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