Evidence for combinatorial variability of tenascin-C isoforms and developmental regulation in the mouse central nervous system.

doi:10.1074/jbc.274.24.17144

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Article

Evidence for combinatorial variability of tenascin-C isoforms and developmental regulation in the mouse central nervous system.

The Journal of biological chemistry - 11 Jun 1999

Joester A, Faissner A

Abstract excerpt

The extracellular matrix glycoprotein tenascin-C (TN-C) displays a restricted and developmentally regulated distribution in the mouse central nervous system. Defined modules of the molecule have been shown to mediate specific functions, such as neuron migration, neurite outgrowth, cell adhesion, and cell proliferation. The smallest TN-C form contains a stretch of eight fibronectin type III (FNIII) domains, which...

Topics

Alternative Splicing
Animals
Base Sequence
Brain
Brain Chemistry
Cerebellum
Fibronectins
Gene Expression Regulation, Developmental
Genetic Variation
Mice
Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Neuroglia

Neurons

Peptide Fragments

Protein Isoforms

Reverse Transcriptase Polymerase Chain Reaction

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 10358070
DOI: 10.1074/jbc.274.24.17144

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