Article
Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma.
Blood - 15 Oct 2006
Chng Wee J, Schop Roelandt F, Price-Troska Tammy, Ghobrial Irene, Kay Neil, Jelinek Diane F, Gertz Morie A, Dispenzieri Angela, Lacy Martha, Kyle Robert A, Greipp Philip R, Tschumper Renee C, Fonseca Rafael, Bergsagel Peter Leif
Abstract excerpt
Waldenström macroglobulinemia (WM) is a B-cell malignancy characterized by the ability of the B-cell clone to differentiate into plasma cells. Although the clinical syndrome and the pathologic characteristics are well defined, little is known about its biology and controversy still exists regarding its cell of origin. In this gene-expression study, we compared the transcription profiles of WM with those of other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.