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Article

Haplotypes defined by promoter and intron 1 polymorphisms of the COLIA1 gene regulate bone mineral density in women.

The Journal of clinical endocrinology and metabolism - 1 Sept 2006

Stewart Tracy L, Jin Huilin, McGuigan Fiona E A, Albagha Omar M E, Garcia-Giralt Natalia, Bassiti Amelia, Grinberg Daniel, Balcells Susana, Reid David M, Ralston Stuart H

Abstract excerpt

CONTEXT: The COLIA1 gene is a strong candidate for susceptibility to osteoporosis. The causal genetic variants are currently unclear, but the most likely are functional polymorphisms in the promoter and intron 1 of COLIA1. OBJECTIVE: The objective of the study was to determine whether promoter and intron 1 polymorphisms of COLIA1 or haplotypes defined by these polymorphisms regulate bone mineral density (BMD) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16804049
DOI: 10.1210/jc.2005-2651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Haplotypes defined by promoter and intron 1 polymorphisms of the COLIA1 gene regulate bone mineral density in women.PMID 16804049Read ↗

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