Flow cytometric determination of the multidrug resistant phenotype in transitional cell cancer of the bladder: implications and applications.

doi:10.1016/s0022-5347(17)37981-8

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Article

Flow cytometric determination of the multidrug resistant phenotype in transitional cell cancer of the bladder: implications and applications.

The Journal of urology - 1 Oct 1991

Benson M C, Giella J, Whang I S, Buttyan R, Hensle T W, Karp F, Olsson C A

Abstract excerpt

We detail our experience with a monoclonal antibody to detect the cell surface P-glycoprotein product of the multidrug resistance gene (MDR-1) in the human bladder. A total of 32 patients had 44 different specimens analyzed. The samples consisted of 8 normal bladders, 21 transitional cell carcinomas, 1 mucinous adenocarcinoma, 3 P-0 bladder wall specimens and 10 nonmalignant urothelial samples from cystectomies....

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Adult
Aged
Aged, 80 and over
Antibodies, Monoclonal
Carcinoma, Transitional Cell
Cell Line
Child
Drug Resistance
Flow Cytometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Membrane Glycoproteins

Middle Aged

Neoplasm Proteins

Phenotype

Tumor Cells, Cultured

Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 1680203
DOI: 10.1016/s0022-5347(17)37981-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1680203-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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