Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS.

doi:10.1212/01.wnl.0000219756.71928.25

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS.

Neurology - 27 Jun 2006

Fernández-Santiago R, Sharma M, Mueller J C, Gohlke H, Illig T, Anneser J, Münch C, Ludolph A, Kamm C, Gasser T

Abstract excerpt

Individuals homozygous for haplotypes -2578-A/-1154-A/-634-G or -2578-A/-1154-G/-634-G in the promoter/5'UTR of the VEGF gene have a 1.8-fold increased risk of ALS in several European populations. We did not observe any significant association with single markers, or haplotype pairs, in a German sample of 580 sporadic ALS patients and 628 controls. However, the promoter SNP-1154 (rs1570360) was associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germany

Share to Prevalence

Share to Risk Assessment

Share to Sex Distribution

Share to Sex Factors

Share to Statistics as Topic

Share to Vascular Endothelial Growth Factor A

Source

Open in PubMed

Identifiers

PMID: 16801663
DOI: 10.1212/01.wnl.0000219756.71928.25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS.PMID 16801663Read ↗

Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype.Semantic proximity Read ↗

Lack of association between VEGF polymorphisms and ALS in a Dutch population.Semantic proximity Read ↗

VEGF promoter haplotype and amyotrophic lateral sclerosis (ALS).Semantic proximity Read ↗

Preliminary evidence that VEGF genetic variability confers susceptibility to frontotemporal lobar degeneration.Semantic proximity Read ↗

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.Semantic proximity Read ↗

A strong association between VEGF-A rs28357093 and amyotrophic lateral sclerosis: a brazilian genetic study.Semantic proximity Read ↗

[Association between the VEGF -2578С/A polymorphism and amyotrophic lateral sclerosis in a Russian population].Semantic proximity Read ↗

VEGF polymorphisms and serum VEGF levels in Parkinson's disease.Semantic proximity Read ↗

Haplotype analysis of single nucleotide polymorphisms in VEGF gene for vascular dementia.Semantic proximity Read ↗

Vascular endothelial growth factor polymorphisms and risk of Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

Absence of angiogenic genes modification in Italian ALS patients.Semantic proximity Read ↗

-1154G/A and -2578C/A polymorphisms of the vascular endothelial growth factor gene in Tunisian Alzheimer patients in relation to beta-amyloid (1-42) and total tau protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.