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Article

VEGF polymorphisms and serum VEGF levels in Parkinson's disease.

Neuroscience letters - 20 Apr 2011

Mihci Ebru, Ozkaynak Sibel S, Sallakci Nilgun, Kizilay Ferah, Yavuzer Ugur

Abstract excerpt

Accumulated data within the recent years demonstrate that reduced levels of VEGF which is a well known angiogenic molecule might cause neurodegeneration in part by impairing neural tissue perfusion, vasoregulation and normal functioning of perivascular autonomic nerves. Additionally, VEGF has been reported to support neuroprotection in dopaminergic neurons by indirect and direct mechanisms and suppress apoptosis...

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Identifiers

PMID: 21334418
DOI: 10.1016/j.neulet.2011.02.027

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