Article
Molecular and Functional Differences between Heart mKv1.7 Channel Isoforms.
The Journal of general physiology - 1 Jul 2006
Finol-Urdaneta Rocio K, Strüver Nina, Terlau Heinrich
Abstract excerpt
Ion channels are membrane-spanning proteins that allow ions to permeate at high rates. The kinetic characteristics of the channels present in a cell determine the cell signaling profile and therefore cell function in many different physiological processes. We found that Kv1.7 channels from mouse heart muscle have two putative translation initiation start sites that generate two channel isoforms with different...
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