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Article

Substance P and Neurokinin 1 receptor - expression is affected in the ileum of mice with mutation in the W locus.

Journal of cellular and molecular medicine - 1 Jan 2000

Faussone-Pellegrini Maria-Simonetta, Vannucchi Maria-Giuliana

Abstract excerpt

The tachykinin substance P (SP) acts on the gut muscle coat via its preferred receptor, neurokinin 1 (NK1r). In the mouse ileum, NK1r-immunoreactivity (NK1r-IR) was detected in neurons, in the interstitial cells of Cajal at the deep muscular plexus (ICC-DMP) and the myoid cells of the villi. SP-IR was detected in neurons and varicose nerve fibers, which were especially numerous at the DMP and closely associated...

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Identifiers

PMID: 16796816
DOI: 10.1111/j.1582-4934.2006.tb00416.x
PMCID: PMC3933138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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