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Article

Existence of c-Kit negative cells with ultrastructural features of interstitial cells of Cajal in the subserosal layer of the W/W(v) mutant mouse colon.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi - 1 Jan 2015

Tamada Hiromi, Kiyama Hiroshi

Abstract excerpt

Interstitial cells of Cajal (ICC) are mesenchymal cells that are distributed along the gastrointestinal tract and function as pacemaker cells or intermediary cells between nerves and smooth muscle cells. ICC express a receptor tyrosine kinase c-Kit, which is an established marker for ICC. The c-kit gene is allelic with the murine white-spotting locus (W), and some ICC subsets were reported to be missing in...

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Identifiers

PMID: 26004376
DOI: 10.1540/jsmr.51.1
PMCID: PMC5137270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Existence of c-Kit negative cells with ultrastructural features of interstitial cells of Cajal in the subserosal layer of the W/W(v) mutant mouse colon.PMID 26004376Read ↗

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W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity.Semantic proximity Read ↗

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