Article
[Prevalence of methylenetetrahydrofolate reductase C677T mutation among patients with acute ischemic cerebrovascular disease in Aragon].
Anales de medicina interna (Madrid, Spain : 1984) - 1 Apr 2006
Sánchez-Marín B, Grasa J M, Torres M, Calvo M T, Martínez-Jarreta B, García-Erce J A, Giralt M
Abstract excerpt
BACKGROUND: Mutation C677T of the methylenetetrahydrofolate reductase (MTHFR) is the main cause of mild hyperhomocysteinemia. Hyperhomocysteinemia is a recognized risk factor for aterothrombosis. MTHFR C677T patients have higher levels of homocysteine in absence of dietary folates. METHODS: Retrospective study over data from patients studied for MTHFR C677T diagnosed of ischemic stroke (IS) younger 50 or older 50...
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