Article
Sodium butyrate causes reexpression of three membrane proteins on glycolipid-anchoring mutants.
Somatic cell and molecular genetics - 1 Jul 1991
Tisdale E J, Schimenti J C, Tartakoff A M
Abstract excerpt
Murine Thy-1-negative lymphoma mutants synthesize membrane proteins that normally bear glycolipid anchors but do not express these proteins on the cell surface. This phenotype may reflect altered regulation of gene(s) required for anchor biosynthesis. Since tissue culture cells treated with sodium butyrate transcribe new DNA sequences and since these transcripts are translated, it was of interest to determine...
Topics
- Animals
- Antigens, Ly
- Antigens, Surface
- Butyrates
- Butyric Acid
- Cell Line
- Fibroblasts
- Gene Expression
- Glycolipids
- Lymphoma
- Membrane Glycoproteins
- Mice
