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Article

Age-related changes in cochlear gene expression in normal and shaker 2 mice.

Journal of the Association for Research in Otolaryngology : JARO - 1 Sept 2006

Gong Tzy-Wen L, Karolyi I Jill, Macdonald James, Beyer Lisa, Raphael Yehoash, Kohrman David C, Camper Sally A, Lomax Margaret I

Abstract excerpt

The vertebrate cochlea is a complex organ optimized for sound transduction. Auditory hair cells, with their precisely arranged stereocilia bundles, transduce sound waves to electrical signals that are transmitted to the brain. Mutations in the unconventional myosin XV cause deafness in both human DFNB3 families and in shaker 2 (sh2) mice as a result of defects in stereocilia. In these mutant mice, hair cells have...

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Identifiers

PMID: 16794912
DOI: 10.1007/s10162-006-0046-7
PMCID: PMC2504614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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