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Article

Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.

Science (New York, N.Y.) - 29 May 1998

Probst F J, Fridell R A, Raphael Y, Saunders T L, Wang A, Liang Y, Morell R J, Touchman J W, Lyons R H, Noben-Trauth K, Friedman T B, Camper S A

Abstract excerpt

The shaker-2 mouse mutation, the homolog of human DFNB3, causes deafness and circling behavior. A bacterial artificial chromosome (BAC) transgene from the shaker-2 critical region corrected the vestibular defects, deafness, and inner ear morphology of shaker-2 mice. An unconventional myosin gene,...

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Identifiers

PMID: 9603735
DOI: 10.1126/science.280.5368.1444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9603735-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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