Article
Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines.
Cancer research - 15 Jun 1994
Heerdt B G, Houston M A, Augenlicht L H
Abstract excerpt
The architecture of normal colonic mucosa suggest that terminally differentiated epithelial cells near the top of the crypt are extruded into the colonic lumen. Morphological studies have identified apoptotic cells among the differentiated phenotypes near the crypt-lumen interface, suggesting a link between pathways of differentiation, apoptosis, and cellular shedding. We studied these processes in HT29 and SW620...
Topics
- Apoptosis
- Butyrates
- Cell Adhesion
- Cell Differentiation
- Colonic Neoplasms
- Culture Media
- Humans
- Phenotype
- Tumor Cells, Cultured