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Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer Therapy

1 Nov 2022

Abstract excerpt

The colon microbiota is an important player in colorectal cancer (CRC) development, which is responsible for most of the cancer-related deaths worldwide. During carcinogenesis, the colon microbiota composition changes from a normobiosis profile to dysbiosis, interfering with the production of short-chain fatty acids (SCFAs). Each SCFA is known to play a role in several biological processes but, despite their...

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PMID: 36365177
DOI: 10.3390/pharmaceutics14112359

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