Article
Association of polymorphisms in forkhead box C2 and perilipin genes with bone mineral density in community-dwelling Japanese individuals.
International journal of molecular medicine - 1 Jul 2006
Yamada Yoshiji, Ando Fujiko, Shimokata Hiroshi
Abstract excerpt
Evidence suggests the existence of a close relation between lipid metabolism and bone remodeling. We hypothesized that polymorphisms of genes that play a role in lipid metabolism, such as those for forkhead box C2 (FOXC2) and perilipin (PLIN), might affect bone mineral density (BMD). We thus examined the possible relationships between a -512C --> T polymorphism of FOXC2 and a 1243C --> T polymorphism of PLIN to...
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