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Article

Association between low density lipoprotein receptor-related protein 2 gene polymorphisms and bone mineral density variation in Chinese population.

PloS one - 1 Jan 2011

Wang Chun, Hu Yi-Ming, He Jin-Wei, Gu Jie-Mei, Zhang Hao, Hu Wei-Wei, Yue Hua, Gao Gao, Xiao Wen-Jin, Yu Jin-Bo, Ke Yao-Hua, Hu Yun-Qiu, Li Miao, Liu Yu-Juan, Fu Wen-Zhen, Ren Ying, Zhang Zhen-Lin

Abstract excerpt

Low density lipoprotein receptor-related protein 2 gene (LRP2) is located next to the genomic region showing suggestive linkage with both hip and wrist bone mineral density (BMD) phenotypes. LRP2 knockout mice showed severe vitamin D deficiency and bone disease, indicating the involvement of LRP2 in the preservation of vitamin D metabolites and delivery of the precursor to the kidney for the generation of...

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Identifiers

PMID: 22174918
DOI: 10.1371/journal.pone.0028874
PMCID: PMC3235174

Genes

LRP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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