Article
Association of single nucleotide polymorphisms in the promoter region of the pro-opiomelanocortin gene (POMC) with low bone mineral density in adult women.
Journal of human genetics - 1 Jan 2005
Sudo Yoshihiro, Ezura Yoichi, Kajita Mitsuko, Yoshida Hideyo, Suzuki Takao, Hosoi Takayuki, Inoue Satoshi, Shiraki Masataka, Ito Hiromoto, Emi Mitsuru
Abstract excerpt
Among multiple factors influencing osteoporosis, genetic variations involved in bone-mineral metabolism can affect risks predisposing to the disease onset. Here, we studied single-nucleotide polymorphisms (SNPs) in the pro-opiomelanocortin (POMC) gene for possible association with bone mineral density (BMD) among 384 adult Japanese women and observed significant correlation between adjusted BMD and three SNPs in...
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