Article
Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men.
International journal of molecular medicine - 1 May 2007
Yamada Yoshiji, Ando Fujiko, Shimokata Hiroshi
Abstract excerpt
Although bone mineral density (BMD) is a complex trait that is influenced by both genetic and environmental factors, heritability studies in twins and families have shown that genetic factors account for 60-85% of the variance in BMD. We examined the relations of six candidate gene polymorphisms to BMD in community-dwelling women and men. The 2238 subjects (1110 women, 1128 men) were aged 40-79 years and were...
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