Article
Association of polymorphisms in the peroxisome proliferator-activated receptor gamma gene and osteoarthritis of the knee.
Annals of the rheumatic diseases - 1 Oct 2006
Cheng S, Afif H, Martel-Pelletier J, Benderdour M, Pelletier J-P, Hilal G, Haraoui P, Raynauld J-P, Choquette D, Fahmi H
Abstract excerpt
OBJECTIVES: To study the association between two common polymorphisms in the peroxisome proliferator-activated receptor gamma (PPARgamma) gene and susceptibility to, and severity of, osteoarthritis in a French-Canadian population. METHODS: Genomic DNA was obtained from 172 patients with osteoarthritis and 210 ethnically matched healthy controls. Genotyping for the polymorphisms in the PPARgamma gene (Pro12Ala and...
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