Article
Optimizing the detection of hereditary non-polyposis colorectal cancer: an update.
Scandinavian journal of gastroenterology. Supplement - 1 Jan 2006
De Bruin J H F M, Ligtenberg M J L, Nagengast F M, Adang E M M, Van Krieken J H J M, Hoogerbrugge N
Abstract excerpt
Hereditary non-polyposis colorectal cancer (HNPCC) is a dominant inherited disease and accounts for up to 5% of all colorectal cancer (CRC) patients. Despite the optimization of selection criteria and enhancements in molecular techniques for identifying more families with HNPCC, most cases are not recognized. Poor patient recollection of family history and inadequate family history-taking are main causative...
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