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Article

[Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas].

Bulletin du cancer - 1 Apr 2004

Olschwang Sylviane, Bonaïti Catherine, Feingold Josué, Frébourg Thierry, Grandjouan Sophie, Lasset Christine, Laurent-Puig Pierre, Lecuru Fabrice, Millat Bertrand, Sobol Hagay, Thomas Gilles, Eisinger François

Abstract excerpt

BACKGROUND: The HNPCC syndrome (hereditary non polyposis colon cancer) is an inherited condition defined by clinical and genealogical information, known as Amsterdam criteria. In about 70% of cases, HNPCC syndrome is caused by germline mutations in MMR genes, leading to microsatellite instability of tumor DNA (MSI phenotype). Patients affected by the disease are at high risk for colorectal and endometrial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15242312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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