Article
Amino acid sequence of the Amur tiger prion protein.
Virus research - 1 Oct 2006
Wu Changde, Pang Wanyong, Zhao Deming
Abstract excerpt
Prion diseases are fatal neurodegenerative disorders in human and animal associated with conformational conversion of a cellular prion protein (PrP(C)) into the pathologic isoform (PrP(Sc)). Various data indicate that the polymorphisms within the open reading frame (ORF) of PrP are associated with the susceptibility and control the species barrier in prion diseases. In the present study, partial Prnp from 25 Amur...
Topics
- Amino Acid Sequence
- Animals
- Animals, Zoo
- Molecular Sequence Data
- Polymorphism, Single Nucleotide
- Prions
- Sequence Alignment
- Species Specificity
- Tigers
