Article
First report of a novel 108 bp deletion and five novel SNPs in PRNP gene of stray cats and in silico analysis of their possible relation with feline spongiform encephalopathy.
Topics in companion animal medicine - 1 Jan 2000
Güvendi Mervenur, Can Hüseyin, Köseoğlu Ahmet Efe, Erkunt Alak Sedef, Ün Cemal
Abstract excerpt
Prion diseases are fatal neurodegenerative diseases affecting humans and animals. A relationship between variations in the prion gene of some species and susceptibility to prion diseases has been detected. However, variations in the prion protein of cats that have close contact with humans and their effect on prion protein are not well-known. Therefore, this study aimed to investigate the variations of prion...
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