Article
Novel Polymorphisms and Genetic Features of the Prion Protein Gene (PRNP) in Cats, Hosts of Feline Spongiform Encephalopathy.
Genes - 24 Dec 2020
Kim Hyeon-Ho, Kim Yong-Chan, Kim Kiwon, Kim An-Dang, Jeong Byung-Hoon
Abstract excerpt
Prion diseases are fatal neurodegenerative disorders characterized by vacuolation and gliosis in the brain. Prion diseases have been reported in several mammals, and genetic polymorphisms of the prion protein gene (PRNP) play an essential role in the vulnerability of prion diseases. However, to date, investigations of PRNP polymorphisms are rare in cats, which are the major host of feline spongiform...
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