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Article

13C NMR analysis of a developmental pathway mutation in Saccharomyces cerevisiae reveals a cell derepressed for succinate dehydrogenase.

Journal of general microbiology - 1 May 1991

Dickinson J R, Hewlins M J

Abstract excerpt

13C nuclear magnetic resonance (NMR) spectroscopy was used to study the metabolism of [2-13C]acetate in a diploid strain of Saccharomyces cerevisiae homozygous for the spo50 mutation. This mutation results in failure to initiate sporulation and suppresses spd mutations (which cause derepressed sporulation). By analysing the pattern of 13C-labelling in glutamate it was deduced that the glyoxylate cycle is...

Topics

Acetates
Acetic Acid
Citric Acid Cycle
Gluconeogenesis
Glutamates
Glutamic Acid
Glyoxylates
Magnetic Resonance Spectroscopy
Mutation
Saccharomyces cerevisiae
Spores, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Succinate Dehydrogenase

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Identifiers

PMID: 1678004
DOI: 10.1099/00221287-137-5-1033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1678004-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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