Article
Association of polymorphisms in the beta2 and beta3 adrenoceptor gene with polycystic ovary syndrome.
The Journal of reproductive medicine - 1 May 2006
Kurabayashi Takumi, Yahata Tetsuro, Quan Jinhua, Tanaka Kenichi
Abstract excerpt
OBJECTIVE: To investigate polymorphisms of the beta2 and beta3 adrenoceptor (BAR-2 and BAR-3, respectively) genes associated with insulin-resistant polycystic ovary syndrome (PCOS) pathogenesis. STUDY DESIGN: Fifty-nine infertile Japanese women with PCOS and 97 healthy Japanese controls were studied. Blood metabolites and genomic DNA polymorphisms of BAR-2 (Arg16Gly and Gln27Glu) and BAR-3 (Trp64Arg) were...
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