Article
Association of polymorphisms in the beta-2 and beta-3 adrenoceptor genes with risk of colorectal cancer in Japanese.
International journal of clinical oncology - 1 Jun 2001
Takezaki T, Hamajima N, Matsuo K, Tanaka R, Hirai T, Kato T, Ohashi K, Tajima K
Abstract excerpt
BACKGROUND: The adrenergic receptor system is involved in thermogenesis and in the activation of lipid mobilization in fat cells, and polymorphisms in the beta-2 and beta-3 adrenoceptor genes (BAR2 and BAR3) have been reported to be associated with obesity and insulin resistance. To examine links between polymorphisms in these genes and the risk of colorectal cancer in Japanese, we conducted the present...
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