Article
Beta2-adrenoceptor polymorphisms relate to insulin resistance and sympathetic overactivity as early markers of metabolic disease in nonobese, normotensive individuals.
American journal of hypertension - 1 Jul 2005
Masuo Kazuko, Katsuya Tomohiro, Fu Yuxiao, Rakugi Hiromi, Ogihara Toshio, Tuck Michael L
Abstract excerpt
BACKGROUND: The genes responsible for insulin resistance are also candidate genes for insulin resistance-related diseases, such as obesity and hypertension. Functional polymorphisms in the beta2- and beta3-adrenergic receptors have been reported to be associated with diabetes, hypertension, and obesity. To clarify the relevance of the beta-adrenergic receptor polymorphisms to insulin resistance, we studied their...
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